Mascot | Research IT Core Services

Mascot

Description

Mascot is a powerful search engine that uses mass spectrometry data to identify proteins from primary sequence databases. Mascot is unique in that it integrates all of the proven methods of searching, including:

Peptide Mass Fingerprinting, in which the only experimental data are peptide mass values
Sequence Query, in which peptide mass data are combined with amino acid sequence and composition information
MS/MS Ion Search, which uses uninterpreted MS/MS data from one or more peptides

For details on the search algorithm as well as a freely accessible web version (with some limitations on the number of queries that can be submitted at any time) please visit the MatrixScience web site.

Availability

Mascot is installed on a quad-core Linux server and can be accessed at http://research.cchmc.org/mascot/. You will need to obtain a user name and password to access this search engine.

More information

For more information about getting access to Mascot, please contact the license holder, Dr. Ken Greis (UC Genome Research Institute). In case of technical difficulties, please contact BMI Helpdesk

Need Help?

For technical assistance with other research software, email software@bmi.cchmc.org. For basic desktop support or assistance with clinical information systems, call the Cincinnati Children's Service Desk, 513-636-4100, or visit the Information Services CenterLink site. UC employees should call the UCit Help Desk, 513-556-HELP.

A note about UCit software

UC researchers are served with desktop software by UCIT. In many cases this software is licensed specifically to UC employees only (i.e., people who receive paychecks from UC) or must be run on UC-owned or controlled equipment, making it inaccessible to Cincinnati Children's personnel. Please make sure you read the license agreement carefully before you use UC software.

Faculty and students of UC are eligible to purchase software from UC. However, when purchasing from UC, the license agreement states that the software can be installed only on your personally owned or UC-owned computer and not on machines owned by other institutions. Since Children’s Hospital is a separate entity from UC, installing software purchased from UC on CCHMC owned computers is a violation of that license agreement. There is a difference in the price of software purchased from Biomedical Informatics at Children’s Hospital versus from the UC Bookstore. This difference is because UC qualifies for the educational discount whereas Children’s Hospital does not. Although Cincinnati Children’s Hospital is affiliated with UC, we are not a degree granting institution. We are a hospital, therefore we only qualify for the healthcare/non-profit discount.